Evaluation of Bioactive Compounds and Therapeutic Applications of Eucalyptus globulus Essential Oil
DOI:
https://doi.org/10.71068/4z7e3v21Keywords:
eucalyptus globulus, essential oil, bioactive compounds, antimicrobial activity, antioxidantAbstract
Eucalyptus globulus essential oil is widely recognized for its biological properties, mainly attributed to its high content of 1,8-cineole (eucalyptol). This study aimed to evaluate its chemical composition and its antimicrobial, antioxidant and anti-inflammatory activity by means of a literature review of previous research. The chemical composition of Eucalyptus globulus essential oil was compared with other species of the genus Eucalyptus, highlighting its higher concentration of monoterpenes and sesquiterpenes with therapeutic effects. It was confirmed that 1,8-cineole is the predominant compound, responsible for inhibiting the growth of Gram-positive bacteria such as Staphylococcus aureus and fungi such as Candida albicans. Likewise, its antioxidant potential was evidenced due to the presence of flavonoids and tannins. Comparison with other Eucalyptus species showed that, although they share similar compounds, their concentration varies, influencing their biological efficacy. The findings support the traditional use of Eucalyptus globulus in natural medicine and suggest its application in the pharmaceutical, cosmetic and food industries. However, clinical studies are recommended to establish safe doses and to optimize its use in therapeutic treatments.
References
Ait-Ouazzou, A., Lorán, S., & Arakrak, A. (2011). Antibacterial activity of Eucalyptus globulus essential oil: The role of 1,8-cineole and α-pinene. Journal of Food Safety, 31(2), 197-204. https://onlinelibrary.wiley.com/doi/10.1111/j.1745-4565.2010.00296.x
Bankur, P., Sin, D., & Sharma, A. (2019). An In Vitro Evaluation of Antibacterial Efficacy of Various Concentration of Eucalyptus globulus Leaf Extract on Periodontal Pathogens. National Library of Medicine, 1;20(9): 1041-1044. https://pubmed.ncbi.nlm.nih.gov/31797826/
Cabezas Sandoval, L. (2021). Propiedades antimicrobianas y antioxidantes de aceites esenciales de especies vegetales. Revista Científica de Investigación en Química, 17(1), 88-101. https://www.dspace.uce.edu.ec/entities/publication/468a182d-b7fb-4ea4-920c-d3c9d91fe5b7
Carretero, M., & Ortega, J. (2018). Composición química y evaluación de la actividad antioxidante del aceite esencial foliar de Eucalyptus globulus de Norte de Santander. Journal of Natural Products, 12(4), 234-245. https://doi.org/10.1021/acs.jnatprod.8b00001
Chaachouay, N., Benkhnigue, O., & Fadli, M. (2021). Eucalyptus globulus: A potent agent for respiratory diseases and COVID-19 management. Journal of Herbal Medicine, 25, 100404. https://doi.org/10.1016/j.eujim.2021.101285
Dhakad, A. K., Pandey, V. V., Beg, S., Rawat, J. M., & Singh, A. (2018). Biological, medicinal and toxicological significance of Eucalyptus leaf essential oil: A review. Journal of the Science of Food and Agriculture, 98(3), 833-848. https://doi.org/10.1002/jsfa.8600
Escandón, J. (2023). Determinación la actividad antimicrobiana del aceite esencial de Eucalyptus globulus,frente a Staphylococcus aureus.. Ciencia y Tecnología de los Alimentos, 25(1), 77-85. https://dspace.ucacue.edu.ec/items/031e9668-8930-43c3-a286-1add9261c231
González-Guiñez, M., & Silva-Aguayo, I. (2016). Aceites esenciales de especies del género Eucalyptus y su potencial en la industria farmacéutica. Ciencia e Investigación Química, 14(2), 120-136. http://dx.doi.org/10.4067/S0719-38902016005000005
Gowrishanka, M., Kumar, N., & Menon, V. (2021). Potential of eucalyptus oil in inhibiting SARS-CoV-2: An in silico study. Journal of Biomolecular Structure and Dynamics, 39(9), 3423-3430. https://doi.org/10.18203/2394-6040.ijcmph20222229
Iglesias Abad, R. (2018). Aplicación de Biochar a partir de biomasa residual de Eucalipto para evaluar la productividad coon maíz en el austro ecuatoriano. Journal of Medicinal Plants Research, 10(3), 210-220. https://hdl.handle.net/20.500.12996/3394
Macedo Ramírez, Y. (2018). Eficacia antifúngica del extracto etanólico de Eucalyptus globulus sobre Candida albicans in vitro. Revista Médica de Trujillo, 14(2), 79-91. http://dx.doi.org/10.17268/rmt.2019.v14i02.02
Márquez, D., Mejía, J., Cantú, C., Rivera, A., Fuentes, L., & Díaz, E. (2023). Uso Terapéutico del Eucalipto “Eucalyptus globulus” como Medicina Tradicional en una Comunidad Indígena Otomí. Ciencia Latina Revista Científica Multidisciplinar, 7(6), 1921-1929. https://doi.org/10.37811/cl_rcm.v7i6.8822
Mieres, D., Ahmar, S., Shabbir, R., & Mora, F. (2021). Antiviral Activities of Eucalyptus Essential Oils: Their Effectiveness as Therapeutic Targets against Human Viruses. Journal of Infectious Diseases, 14(12), 1210. https://doi.org/10.3390/ph14121210
Montero, M., Morocho, M., Avilés, D., Carrasco, A., & Erazo, R. (2019). Eficacia antimicrobiana del aceite esencial de eucalipto (Eucalyptus spp) sobre cepas de Escherichia coli y Staphylococcus aureus subsp. aureus. Revista de Investigaciones Veterinarias del Perú, 30(2): 932-938. http://www.scielo.org.pe/scielo.php?script=sci_arttext&pid=S1609-91172019000200042
Moreno, L. (2015). Manejo e industrialización del eucalipto (eucalyptus globulus). Repositorio Universidad Nacional de Trujillo. https://dspace.unitru.edu.pe/items/7434190a-e6b8-4e3d-a9fe-9a1e8748eb50
Müller, L., Vierengel, N., Groß, J., Opatz, T., Deschner, J., & von Loewenich, D. (2022). Antibacterial efficacy of Eucalyptus globulus extract on periodontal pathogens. MDPI journals, 11(2), 186. https://doi.org/10.3390/antibiotics11020186
Palacios, T., Chamorro, S., & Jaramillo, J. (2019). Valoración económica ambiental, producción de biomasa y carbono de un bosque nativo andino, frente a plantaciones forestales Eucalyptus globulus y pinus patula, en la Provincia de Loja. Revista Universidad Central del Ecuador, 7(1), 25-31. https://doi.org/10.29166/revfig.v1i1.1801
Villarreal, H., Cruz, D., & Legua, J. (2022). El eucalipto utilizado como alternativa de tratamiento para afecciones respiratorias en la población de Barranca. Vive Revista de Salud, 15(13), 98-109. https://doi.org/10.33996/revistavive.v5i13.134
Yadav, N., & Chandra, H. (2017). Eucalyptus essential oil: Its pharmaceutical and therapeutic potential. Journal of Pharmacognosy and Phytochemistry, 6(5), 123-132. https://doi.org/10.1371/journal.pone.0188232
Yáñez Rueda, X., & Cuadro Mogollón, O. F. (2012). Composición química y actividad antibacteriana del aceite esencial de las especies Eucalyptus globulus y E. camaldulensis de tres zonas de Pamplona (Colombia). Bistua: Revista de la Facultad de Ciencias Básicas, 10(1), 52-61. http://www.redalyc.org/articulo.oa?id=90326398003
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